interdisciplinary research


ICT meets BIO & NANO

  • Molecular Communications for

    First workshop at the intersection of molecular communications and synthetic biology towards wetware artificial life.
    (co-organized by CALICO Lab at ALIFE'23

  • Special Feature on

    From molecular cybernetics to network medicine: Interdisciplinary synergies in molecular communications and Internet of Bio-Nano Things. (co-organized by CALICO Lab in IEEE TMBMC)

  • Molecular Communications getting practical with


    We report on the fabrication of the first micro/nanoscale MC receiver based on graphene field-effect transistor biosensors.

  • Join us!

    Applications are invited for fully-funded MSc and PhD student positions!

  • New Project

    Our project 'REINFORMATION' has been awarded the MSCA Individual Fellowship!

  • New Project

    Our project 'MiMoGraph' has been awarded the TUBITAK 1001 Grant!

[new project] Our project ‘REINFORMATION‘ has been awarded the MSCA Individual Fellowship! [Learn more]

[join us!]
Applications are invited for fully-funded MSc and PhD positions!  

[Learn more]

[new project] Our project ‘MiMoGraph‘ has been awarded the TUBITAK 1001 grant! [Learn more]

[Molecular Communications getting practical with GRAPHENE]
We report on the first micro/nanoscale MC receiver based on graphene.
[See recent publications]

nano/bio/physical information and communications laboratory

Our current research activities at CALICO Lab revolve around the Internet of Bio-Nano Things (IoBNT), an emerging information and communication technology (ICT) framework aiming at extending our connectivity and control to NANOscale and BIOlogical environments with collaborative networks of artificial nanomachines and biological entities.

At the intersection of ICT, nanotechnology and biotechnology, we conduct highly interdisciplinary theoretical and experimental research with the objective of realizing the futuristic medical, environmental, and industrial applications of the IoBNT. 

IoBNT is nonconventional in every respect: nonconventional things (e.g., engineered bacteria, nanobiosensors, nanoparticles) coordinated via nonconventional communication methods (e.g., molecular communications) in nonconventional environments (e.g., inside human body) for nonconventional applications (e.g., continuous intrabody health monitoring, smart drug delivery without side effects).

Our quest to develop practical IoBNT applications bears many challenges, that can basically be worded in questions such as

  • How to establish communication between highly heterogeneous bio-nano things, which also happen to be severely limited in size, complexity, and resources
  • How to deal with the adverse effects of nonconventional environments (e.g., fluctuating physiological conditions) on communication
  • How to seamlessly interface IoBNT with conventional macroscale networks
  • How to ensure the coexistence of artificial IoBNT with natural IoBNT (e.g., cell signaling) in a compatible manner
  • How to leverage the communication of bio-nano things to further expand the economic and societal impact of IoBNT with novel applications

To target these challenges, we follow a highly interdisciplinary methodology integrating expertise in ICT, molecular communications, microfluidics, nanobiosensors, graphene and related nanomaterials. We are currently

  • building realistic models for molecular communications (MC), supported by finite-element and particle-based spatial stochastic simulations
  • designing new MC transceivers enabled by novel nanomaterials (e.g., graphene) and synthetic biology tools
  • fabricating microfluidic MC testbeds with micro/nanoscale MC transceivers
  • developing practical and low-complexity modulation, detection and channel estimation techniques by exploiting unique properties of nanoscale and biological interactions, e.g., ligand-receptor interactions
  • exploring new nano/macro and bio/cyber interfaces
  • and searching for new nanocommunication paradigms, e.g., FRET-based nanocommunication

Just as the overarching endeavour of space exploration has given rise to countless spinoff technologies exploited mostly in other areas, e.g., cochlear implants and CMOS image sensors, so our interdisciplinary quest to develop practical IoBNT applications is hoped to have far-reaching impact on, for example, microfluidic drug delivery, biosensing for dynamic biomarkers, ICT understanding of biological systems, multiplexed biosensing, development of new diagnosis and treatment techniques, and many more.

We are now recruiting
MSc and PhD students!