Ligand-receptor (LR) interactions are essential for artificial molecular communication (MC) systems to have a selective and reliable channel/receiver interface in the form of a biorecognition layer consisting of ligand receptors. Recent studies have revealed the dramatic impact of LR interactions on the overall MC performance in terms of channel bandwidth, molecular interference, receiver sensitivity and dynamic range, posing a multi-objective optimisation problem. The aim of REINFORMATION is to understand, optimise and engineer the LR interactions for high data-rate and reliable MC systems.